A rabbit model of toxic shock syndrome that uses a constant, subcutaneous infusion of toxic shock syndrome toxin 1
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چکیده
منابع مشابه
Toxicity of recombinant toxic shock syndrome toxin 1 and mutant toxins produced by Staphylococcus aureus in a rabbit infection model of toxic shock syndrome.
Menstrually associated toxic shock syndrome (TSS) is attributed primarily to the effects of staphylococcal exotoxin toxic shock syndrome toxin 1 (TSST-1). A region of the 194-amino-acid toxin spanning residues 115 through 144 constitutes a biologically active site. Several point mutations in the TSST-1 gene in that region result in gene products with reduced mitogenic activity for murine T cell...
متن کاملIdentification of Toxic Shock Syndrome Toxin-1 (TSST-1) gene in Staphylococcus aureus isolated from bovine mastitis milk
Staphylococcus aureus is a major causative pathogen of clinical and subclinical mastitis of dairy domestic ruminants. This agent produces a variety of extracellular toxins and virulence factors including Toxic Shock Syndrome Toxin-1 (TSST-1) which is the major cause of Toxic Shock Syndrome (TSS). In this study 58 S. aureus isolates obtained from 9 dairy herds in East and West Azerbaijan provinc...
متن کاملToxic shock syndrome
Toxic shock syndrome is an acute febrile illness with mucocutaneous manifestations and multisystem involvement, often associated with focal staphylococcal infection. Although Todd originally described the disorder in children,' with a subsequent report of childhood toxic shock syndrome,2 publicity given to the disorder in relation to menstruation and tampon use has resulted in its being conside...
متن کاملToxic shock syndrome.
The entity of the variable pictures of an illness summed up by the description "toxic shock syndrome" has been focussed on by a great number of publications in Northern America since 1978, but has been described scarcely until yet in Germany. An etiological relationship with formerly described "toxic scarlet fever" and "Kawasaki syndrome" is to be discussed. This case in charge deals with a 25-...
متن کاملToxic Shock Syndrome (TSS)
Toxic Shock Syndrome, otherwise known as TSS, is a systemic infection that is associated with the bacteria Staphylococcus aureus [1]. S. aureus exists as part of the human body’s normal bacteria, and does not cause infection since most people develop antibodies against the bacteria. Infection can be result in people that have not developed these antibodies, or may develop in people that have an...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 1987
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.55.5.1070-1076.1987